Generally, the greatest impact of sexuality on the developmental stages of an individual is experienced during adolescence and young adulthood. In adolescence, development attempts to figure out identity, establish goals and priorities for adult life and this often leads to an identity crisis. Beyond adolescence, young adulthood developmental stage attempts to establish and build upon relationships culminating in intimacy or isolation. Navigating through these developmental stages depends on the individual’s moral framework which is in-turn modelled by the individual’s ethical framework. Ethics refers to what distinguishes right from wrong in the way people interact with the real world and an ethical framework is a set of codes that an individual uses to guide his or her behavior. Therefore, individuals may make different moral judgments on the same situation and what one thinks is the best solution for a particular problem is his or her moral framework. Generally, cultures and therefore languages have individual moral framework. However, it is known that guidelines on ethical practice in research and education of these vulnerable groups is hinged upon protection from potential sexual, economic, emotional and political exploitation (the four pillars). Ethical guidelines mandate additional protective measures for minors because of power relations between adults and children which exposes their inherent vulnerability, for example, to sexual exploitation. Therefore, while the aforesaid four pillars warrant attention, we argue that language and cultural perspectives must be integrated into the moral framework for education and learning in diverse mainstream languages. Through an analysis of mainstream languages and cultures in Zimbabwe as well as engagement of language experts, learners and educators in an ethnographic study, we show draw up an integrated moral framework for Zimbabwe on the appropriateness of indigenous languages in sexuality education. We conclude that sexuality education must be taught in indigenous languages only after contextualization into the aforesaid moral framework otherwise imbedded norms and contradictions that shape relationships will promote unintended extrapolations. It is recommended that, where these extrapolations emerge, further research must focus on contextual approach to insight people’s everyday ethical practice, norms and values motivating their decisions.