Introduction: Vaccination-related myocarditis has been reported as a major side effect of the mRNA COVID-19 vaccine. In this review article, a series of 15 global case reports of laboratory-confirmed myocarditis post COVID-19 vaccination were summarized. Objectives: The main objective of this article is to critically analyze and summarize published case reports on vaccination-associated myocarditis. Methodology: Google Scholar was used to search for confirmed cases of vaccination-associated myocarditis from 2021 to 2022. Results: It was found that there is a higher prevalence of immunization-related myocarditis in young adults, especially in male patients (94%). Genetic defects, environmental aspects and dietary habits were discovered as other factors that could have stimulated the development of myocarditis.Troponin and C-reactive protein levels were elevated in most cases (93%). Conclusions: vaccination-associated myocarditis case reports are very rare and only represent a minimal fraction of the total population that has been vaccinated. The benefits offered by the COVID-19 vaccine far outweigh the effects a COVID-19 infection. It is recommended to continue administering the mRNA vaccine to manage the COVID-19 pandemic.